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Thursday 20 January 2011

Mammoth 'could be reborn in four years'

The woolly mammoth, extinct for thousands of years, could be brought back to life in as little as four years thanks to a breakthrough in cloning technology.

Previous efforts in the 1990s to recover nuclei in cells from the skin and muscle tissue from mammoths found in the Siberian permafrost failed because they had been too badly damaged by the extreme cold.

But a technique pioneered in 2008 by Dr. Teruhiko Wakayama, of the Riken Centre for Developmental Biology, was successful in cloning a mouse from the cells of another mouse that had been frozen for 16 years.

Now that hurdle has been overcome, Akira Iritani, a professor at Kyoto University, is reactivating his campaign to resurrect the species that died out 5,000 years ago.

"Now the technical problems have been overcome, all we need is a good sample of soft tissue from a frozen mammoth," he told The Daily Telegraph.

He intends to use Dr Wakayama's technique to identify the nuclei of viable mammoth cells before extracting the healthy ones.

The nuclei will then be inserted into the egg cells of an African elephant, which will act as the surrogate mother for the mammoth.

Professor Iritani said he estimates that another two years will be needed before the elephant can be impregnated, followed by the approximately 600-day gestation period.

He has announced plans to travel to Siberia in the summer to search for mammoths in the permafrost and to recover a sample of skin or tissue that can be as small as 3cm square. If he is unsuccessful, the professor said, he will ask Russian scientists to provide a sample from one of their finds.

"The success rate in the cloning of cattle was poor until recently but now stands at about 30 per cent," he said. "I think we have a reasonable chance of success and a healthy mammoth could be born in four or five years."

215 comments
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Yesterday 05:17 AM
Recommended by
1 person
I wonder what it would taste like....
J.P. Craig-Weston
Yesterday 09:28 AM
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2 people
Chicken
rmthunter
01/17/2011 11:29 PM
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1 person
Hmm -- just when we're losing the Arctic.

Timing is everything.
01/18/2011 12:32 PM
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3 people
Not to worry. England's climate will suit them if recent weather is the norm.
01/17/2011 09:31 PM
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1 person
This just shows the turbidity of modern science' vision; lets resurrect a beast evolved for cold weather just when the world will be getting at it's warmest, and for what reason? Other than to sell merchandise for an abomination of a 21st century circus side-show. I'm really beginning to believe humanity has an insipid sense of direction. Maybe we could clone these with Nike swoosh' in place of tusks.
01/18/2011 05:14 AM
Don't worry, we'll kill ourselves off shortly after, and not be able to harass living creatures for much longer.
The Solar Maximum will ruin technology, and then a bunch of crap involving a mass panic by the addicts cause the 'end of the world'.
01/17/2011 07:00 PM
I'm not sure that this would serve any purpose. The species was presumably defunct and upgraded to more modern versions.
Also think of of the arguably very sad circumstances which the first said animal would have to endure. Fame is not necessarily fun.
01/17/2011 03:19 PM
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1 person
Uhm, NO! Dear Scientists - we know you CAN do this, but SHOULD you do this? I mean, Sabretooth tigers, sure, but Mammoths, NO! Also, didn't you see Jurassic Park - it ends badly!
01/17/2011 03:39 PM
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3 people
Im not sure you and I saw the same movie. There was NO Mammoths in Jurassic Park I, II or III
01/17/2011 11:58 AM
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1 person
It should be noted that frozen for 16 years and for 5,000 years is a pretty significant difference. Quite a lot of DNA damage can accumulate in that time just from simple things like exposure to UV rays...
Scientifically, it's fascinating. But otherwise useless.
Yesterday 10:45 AM
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1 person
Why do you think that this would be useless? There must be potential gains to be had from harnessing such a potent capability - even if the current end goal of bringing back an extinct mammal doesn't appear to serve any worthy purpose.

Aside from the technical achievements that I assume will be made by the project, it also offers a chance to question ideas and concepts that are generally considered definitive - such as extinction.
Tony R.
01/17/2011 08:51 AM
Recommended by
10 people
Forget about global warming. This is a welcome development, just in time for the coming Ice Age. It's going to get very cold, and we'll need something to eat after all the cows and chickens freeze to death.
minamisan
01/16/2011 07:52 AM
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8 people
Somewhere in Hong Kong, a billionaire property developer is thinking of ways to get one of these on a dinner plate.
01/16/2011 07:39 AM
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6 people
This is goo news. They now ony need to do the same with Neanerthals and we have a supply of cheap abour.
Physics grad
01/16/2011 10:23 PM
Recommended by
4 people
plus Neanderthals are probably smarter than most liberals so we could use them to replace civil servants and finally balance the budget...
01/17/2011 11:07 PM
Recommended by
5 people
Is the name "Physics grad" an instance of aspirational naming? Similar to how some Asian families will name their child Dollar or Harvard in the hopes that it will lead to future success?
01/17/2011 03:39 PM
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2 people
LOL Good one!
Steve Rogers
01/17/2011 10:21 AM
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3 people
Every published study says that liberals are smarter than conservatives. IQ-wise, about 12% smarter on average. Look it up on that picture-typey thing in front of you.

If you check out the bell curve, you can see that Ted Nugent and Neanderthals are neck and neck at the far reaches of the left end.
superpeople
01/17/2011 12:12 AM
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3 people
OMG soooo funny... and clever. You_must_have a huge brain. It's true civil servants all across the world are the cause of the deficit. How has no one mentioned this until now? Be my friend?
01/16/2011 04:16 AM
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1 person
The new expression will be "they avoided the subject even though it was like a mammoth sitting in the room".

Or "pet mammoths" just like the Hollywood stars... or Tony Blair was George Bush's "lap mammoth".
01/16/2011 04:16 AM
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1 person
Wouldn't an Asian Elephant make more sense? Last I heard that was the mammoths closest relative. Why african I wonder...
01/17/2011 03:40 PM
African Elephant is just the carrier.
01/16/2011 04:15 AM
Recommended by
2 people
Exbrat, you don't know your science. T Rex could not be cloned like this. 1818simax18 it would live in a zoo and the zoo would make a fortune by charging people to see it, including me.
J.P. Craig-Weston
01/16/2011 12:40 PM
Recommended by
1 person
and me.
01/17/2011 03:47 PM
me too!
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DrChrisThomasLA
Today 02:11 AM
From twitter via BackType
RT @AVMAvets: A new species for veterinarians to care for? Japanese scientist says wooly mammoth could be cloned within 5 years http://bit.ly/g4U9ZD
dpim
Yesterday 11:37 PM
From twitter via BackType
Cloning Mammoths? Science is so cool. http://bit.ly/fJLHzh
CounterReligion
Yesterday 11:36 PM
From twitter via BackType
Challenge: Dear God Can Make a Mammoth Reborn Supernaturally in Less than 4 tears? http://fb.me/FaG2ugV7
marhis_
Yesterday 09:26 PM
From twitter via BackType
Mammoth 'could be reborn in four years' - claimed @telegraph almost a week ago http://bit.ly/fgWw6L what does @mammut say about this one?
missb62
Yesterday 09:25 PM
From twitter via BackType
RT @djamila617: Paging Steven Spielberg--Bring on Cenozoic park. 'Mammoth could be reborn in four years' - Telegraph http://t.co/2KaNDVU via @Telegraph
djamila617
Yesterday 09:15 PM
From twitter via BackType
Paging Steven Spielberg--Bring on Cenozoic park. 'Mammoth could be reborn in four years' - Telegraph http://t.co/2KaNDVU via @Telegraph
DDsD
Yesterday 09:02 PM
From twitter via BackType
RT @tsuken: Cool - but kind of weird too: Mammoth 'could be reborn in four years' - Telegraph http://is.gd/YdijxS #fb
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